Third-Generation Chemist Kyubee summary: "I want to believe in my first love. But then we met." 25-year-old Miku, who moved back to the house she grew up in two months ago, is studying to succeed her grandfather's Chinese medicine store, "Kusuriya Kyubee." Everyday she and her grandfather respond to the troubles of the customers who visit the store, prepare herbal medicine for them, or simply chat with them. On the other hand, Miku is unable to forget her first love, but she meets an ultra-shy boy named Kanae who likes plants. Perhaps she is beginning to care about him little by little.